WP3

WP3

Upscaling from cells to tissue

Structures in soft tissue are rarely periodic, yet many upscaling techniques use homogenisation based on this periodic assumption. We will develop improved upscaling methods independent of the assumption of periodicity and validate them against specifically-designed cellular and tissue experiments.

Project 1: Micro to mesoscale framework and Meso to macroscale framework

Project 2: Growth & Remodelling framework

Project 3: Evaluation of models by development of modules with Simulia (link to the company) and Ansys (link to the company)

 

Team:  Prof. Hill, Prof. Ogden, Prof. Chaplain, Dr. Stewart, Dr. Watton, Dr. Yin, Prof. Olson, Prof. Luo,
Prof. Husmeier, PDRA3, PhD4